Effect of Purple Sweet Potato Extract Administration on Total Cholesterol Level of Diabetic and High Fat Diet Wistar Rats

Diabetes is a disease correlated with the damage of b-pancreatic cells, due to increasing number free-radicals in body, causing body failed produce insulin normal degree, cannot function effectively. In general, diabetic patients suffered from lipid metabolism distortion that would increase total cholesterol level imbalance between and endogenous antioxidants. Purple sweet potato has high antioxidant level. This research aims compare treatment non-treatment (without purple extract administration) groups. It an experimental laboratory. The trial animal was 30 male Wistar rats assigned 6 groups, including diet group, fat STZ group diet, dose 1 (0/75 ml/200g BW), 2 (1.5 ml/200 g metformin group. results show yield macerated 95%: acetic acid: water (25:1:5) 46.98%. average, 61.3 mg/dL, 63 81.3 63.3 58 65.66 mg/dL. conclusion, there no significant difference each sig value 0.0408 < 0.05. lowest administered II BW).